Comparison of Corticosteroids
This chart and data was extracted from Goodman and Gilman: "The Pharmacological Basis of Therapeutics."
Its purpose is to help users of corticosteroids understand the potency and other differences of all the commonly long-acting and short-duration corticosteroids. The list includes all of the following corticosteroids: Solu-Cortef® (Hydrocortisone Sodium Succinate), Kenalog® 40 (Triamcinalone Acetonide), Aristospan® (Triamxinolone Hexatonide), Celestone® Soluspan® (Betamethasone Sodium Phosphate & Betamethasone Acetate), Depo Medrol®-40 (Methylprednisolone Acetate), Depo Medrol®-80 (Methylprednisolone Acetate), Solu-Medrol® (Methylprednisolone Sodium Succinate), and Dexamethasone Sodium Phosphate.
| Product (Chemical Name) |
mg/ml | Anti-inflam. Potency | Potency Expressed in Hydrocortisone Equivalency (mg) | Contains Benzyl Alcohol | Route of Admin. | Average Dosage |
|---|---|---|---|---|---|---|
| Solu-Cortef® Hydrocortisone Sodium Succinate | 50 | 1 | 50 | No | IM or IV | See Insert |
| Celestone Soluspan® Betamethasone Sodium Phosphate & Betamethasone Acetate | 3 + 3 | 25 | 150 | No | IM, IA, IL & Soft Tissue | 0.25–2 ml |
| Kenalog®-40 Triamcinolone Acetonide | 40 | 5 | 200 | Yes | IM, IA & Soft Tissue | 0.25–2 ml |
| Depo-Medrol®-40 Methylprednisolone Acetate | 40 | 5 | 200 | SDV-No / MDV-Yes | IM, IA, IL & Soft Tissue | 0.25–2 ml |
| Depo-Medrol®-80 Methylprednisolone Acetate | 80 | 5 | 400 | SDV-No / MDV-Yes | IM, IA, IL & Soft Tissue | 0.25–2 ml |
| Dexamethasone Sodium Phosphate | 4 | 25 | 100 | Yes | IM, IV, IA, IL & Soft Tissue | See Insert |
| Dexamethasone Sodium Phosphate Preservative Free | 10 | 25 | 250 | No | IM or IV | See Insert |
| Solu-Medrol® Methylprednisolone Sodium Succinate | 40 | 5 | 200 | No | IM or IV | See Insert |