| |
Comparison of
Parenteral Corticosteroids
|
PRODUCT (Chemical Name) |
mg/ml |
DOSAGE |
POTENCY Expressed in Hydrocortisone Equiv. per ml |
ROUTE of ADMINISTRATION |
TYPE |
|
** Aristocort Forte®
NOT AVAILABLE (Triamcinolone Diacetate) |
40 |
1/4 to 2 ml |
200 |
IM, IA
& Soft Tissue |
Long Acting |
|
** Kenalog® "40" (Triamcinolone Acetonide) |
40 |
1/4 to 2 ml |
200 |
IM, IA
& Soft Tissue |
Long Acting |
|
** Aristospan®
(Triamcinolone Hexacetonide) |
20 |
1/4 to 2 ml |
100 |
IA & Soft Tissue
IM,ID,IL |
Long Acting |
|
** Celestone Soluspan® (Betamethasone Sod-Phosphate & Betamethasone Acetate) |
3+3 |
1/4 to 2 ml |
150 |
IM, IA, IL
& Soft Tissue |
Rapid
and Long Acting |
|
Depo Medrol® (Methylprednisolone Acetate) |
40 |
1/4 to 2 ml |
200 |
IM, IA, IL
& Soft Tissue |
Long Acting |
|
** Decadron L.A. (Dexamethasone Acetate)
NOT AVAILABLE |
8 |
1/4 to 2 ml |
200 |
IM, IA, IL
& Soft Tissue |
Long Acting |
|
Solu-Medrol®
(Methylprednisolone Sodium Succinate) |
40 |
See Insert |
200 |
IM or IV |
Rapid Acting |
|
Dexamethasone (Sodium Phosphate) |
4 |
See Insert |
100 |
IM, IV, IA, IL
& Soft Tissue |
Rapid Acting |
|
Dexamethasone (Sodium Phosphate) |
10 |
See Insert |
250 |
IM or IV |
Rapid Acting |
**There Are NO FDA APPROVED GENERICS Currently Being Manufactured For These Products.
For more information relating to the dangers of compounding; go to the Clint NEWS Page or see July 2nd, 2001 article titled "FATAL MENINGITIS LINKED TO COMPOUNDING" at DRUGTOPICS.COM.
Data on the chart above was extracted from: Goodman and Gillman "The Pharmacological Basis of Therapeutics".
|
|
|
Aristospan® |
Depo-Medrol® |
|
Indicated for Intra-Articular Injection |
YES (1) |
YES (1) |
|
% Solubility in Water at 25 Degrees C |
0.0002 Least
Soluble (2) |
0.0014 (2) |
|
Duration of Palliation |
21.2 days/20mg (3) |
8.2 days/30mg (3) |
|
May be mixed with Lidocaine
in same vial or syringe |
YES (1) |
Should NOT be mixed
with other Solutions (1) |
|
May be mixed with PRESERVATIVE FREE ANESTHETICS w/o FLOCCULATION of SUSPENSION |
YES (1) |
NO (1) |
|
Available drug concentration
for multidose vials |
20mg/ml (1) |
80mg/ml
40mg/ml (1) |
|
Required Dose: Large Joints
Small Joints |
10-20 mg
2-6mg (1) |
20-80m r> 4-10mg (1) |
|
Average Reimbursement
Per mL at code price |
$12.96 (4) |
$9.92 (4) |
| Chart Key: |
(1) See Respective Package Insert
(2) Lederle Laboratories; April, 1988
(3) Hollander JL., Maryland State Medical Journal; 1970
(4) Reimbursementcodes.com (May 2004) Reimbursement varies /
Check for accuracy |
|
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