PRODUCT (Chemical Name) |
mg/ml |
DOSAGE |
POTENCY (when compared with Hydrocortisone ml to ml) |
HYDRO- CORTISONE Equivalency (per ml) |
ROUTE of Administration |
TYPE |
**Kenalog® "40" (Triamcinolone Acetonide) |
40 |
1/4
- 2ml |
5 |
200 |
IM,
IA & Soft Tissue |
Long
Acting |
** Aristospan® (Triamcinolone Hexacetonide) |
20 |
1/4
- 2 ml |
5 |
100 |
IA & Soft
Tissue IM,ID,IL |
Long
Acting |
Celestone
Soluspan® (Betamethasone Sod-Phosphate & Betamethasone Acetate) |
3+3 |
1/4
- 2ml |
25 |
150 |
IM,
IA, IL & Soft Tissue |
Rapid and Long Acting |
| Depo
Medrol®-40 (Methylprednisolone Acetate) |
40 |
1/4
- 2ml |
5 |
200 |
IM,
IA, IL & Soft Tissue |
Long
Acting |
| Depo
Medrol®-80 (Methylprednisolone Acetate) |
80 |
1/4
- 2ml |
5 |
400 |
IM, IA, IL & Soft Tissue |
Long Acting |
Solu-Medrol® (Methylprednisolone Sodium Succinate) |
40 |
See Insert |
5 |
200 |
IM
or IV |
Rapid
and Short Duration |
Solu-Medrol® PRESERVATIVE
FREE (Methylprednisolone Sodium Succinate) |
62.5 |
See Insert |
5 |
312.5 |
IM or IV |
Rapid
and Short Duration |
Dexamethasone (Sodium Phosphate) |
4 |
See Insert |
25 |
100 |
IM, IV, IA, IL & Soft Tissue |
Rapid
and Short Duration |
Dexamethasone PRESERVATIVE
FREE (Sodium Phosphate) |
10 |
See Insert |
25 |
250 |
IM or IV |
Rapid
and Short Duration |
**There Are NO FDA APPROVED GENERICS Currently Being Manufactured For These Products.
Aristospan® |
Depo-Medrol® |
|
Indicated for Intra-Articular Injection |
YES (1) |
YES (1) |
% Solubility in Water at 25 Degrees C |
0.0002 Least Soluble (2) |
0.0014 (2) |
Duration of Palliation |
21.2 days/20mg (3) |
8.2 days/30mg (3) |
May be mixed with Lidocaine in same vial or syringe |
YES (1) |
Should NOT be mixed with other Solutions (1) |
May be mixed with PRESERVATIVE FREE ANESTHETICS w/o FLOCCULATION of SUSPENSION |
YES (1) |
NO (1) |
Available drug concentration for multidose vials |
20mg/ml (1) |
80mg/ml 40mg/ml (1) |
Required Dose: Large Joints Small Joints |
10-20 mg 2-6mg (1) |
20-80m r> 4-10mg (1) |
Average Reimbursement Per mL at code price |
$12.96 (4) |
$9.92 (4) |
For more information relating to the dangers of compounding; go to the Clint NEWS Page or see July 2nd, 2001 article titled "FATAL MENINGITIS LINKED TO COMPOUNDING" at DRUGTOPICS.COM. Data on the chart above was extracted from: Goodman and Gillman "The Pharmacological Basis of Therapeutics".
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